Fareston A Drug Used In Breast Cancer And In Treatment For Athletes and Bodybuilders
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One of the treatments used for breast cancer is a drug that goes under the brand name of Fareston. The chemical name for Fareston is Toremifene Citrate. Fareston belongs to a class of drugs known as Selective Estrogen Receptor Modulators (SERM), and it is called a nonsteriodal antiestrogen. Fareston is similar to other classes of breast cancer medication, such as Nolvadex (Tamoxifen) and Clomid. Fareston is used as a successful breast cancer treatment for post-menopausal women. Fareston, like Nolvadex will act as an antagonist against estrogen production in breast tissue. The female hormone estrogen is responsible for developing female reproductive organs and genitalia. However, even though estrogen is vital to the appearance of a female and the biological functionality of women, estrogen, which attaches to cell receptors, is also a factor in breast cancer. Nolvadex, the Selective Estrogen Modulator is often given to male bodybuilders who want to avoid the abnormal growth of breast tissue (gynocomastia).
Fareston and the function of Selective Estrogen Receptor Modulators
When we look at the male anatomy we must start with the hypothalamus and the pituitary where estrogen will aid in the body’s negative feedback loop, which sends a signal to the pituitary to reduce the secretion of the luteinizing hormone (LH). When the luteinizing hormone is decreased, what happens is that it will also have an affect on testosterone levels (the male hormone), which will also be low as well.
Fareston will bind with the estrogen receptors to prevent estrogen production and the growth stimulating affects on cancerous tumors. Fareston can also change the estradiol induced vaginal composition in some postmenopausal women.
Though there are not enough studies to make predictions at this point in time, researchers believe that by keeping the estrogen levels down in males, it will increase the levels of testosterone. This is one of the functions of Nolvadex. Researchers also feel that in the long run Fareston may be more of an affective treatment for male bodybuilders and athletes who are using steroids, than Nolvadex.
Some of the known side affects of this drug include: hot flashes, edema, vomiting and nausea, sweating, dizziness, vaginal discharge or vaginal bleeding in women with breast cancer.
Differences between Fareston and Nolvadex
Even though Fareston and Nolvadex share common properties and benefits, they also differ in some ways. Even though Nolvadex does not have many side affects Fareston has even less. However, even lower than present in Nolvadex, the risks for pulmonary embolism, stroke and cataracts are still present when using Fareston.
People who have floaters in their vision, a side affect of taking Nolvadex or Clomid will not have these issues with Fareston. Floaters are black or gray specks, strings, or anything, which floats around the eyes when the eyes are moving around. Fareston is less toxic to the ocular area. Fareston may be better at improving lipids (cholesterol) profiles. However, the two drugs are about equal in determining bone density.
Though Fareston is used as a breast cancer medication, some people do have a hypersensitivity to the drug. There have been symptoms of hypercalcemia and tumors caused by the drug. There is also pain associated with bone metastases. It is hard to foresee if Fareston actually causes cancerous growth at this time, because Fareston is used as a breast cancer medication in women who already have experienced the spread of cancer to various parts of the body. Also when patients have had different treatments prior to using Fareston, it becomes even more difficult to determine which side affect is attributed to which drug.
Endometriosis has been found in animal who were administered Fareston. It is not recommended that pregnant women use Fareston as this breast cancer treatment may cause harm to the fetus. People with any kind of blood vessel complications such thrombosis should not use this drug. Also if the cancer has already spread to the bones, it is recommended that Fareston not be used.